First approved by the Food and Drug Administration in 1999 to treat type II, or adult onset diabetes, Avandia became one of the most popular drugs for the pharmaceutical company GlaxoSmithKline. It works by allowing the body to use insulin it produces to control the levels of blood sugar in the liver and prevent the serious and potentially fatal aspects of this condition that affects almost 16 million adults in the United States.
Unfortunately, Avandia has been linked to a number of serious side effects of its own. From as early as 2003, medical experts at the Mayo Clinic discovered that Avandia was linked to six cases of congestive heart failure in elderly men undergoing treatment for type II diabetes. These men experienced symptoms of weight gain, swelling of the extremities, shortness of breath, and fluid in the lungs, which all occur when the heart can no longer pump blood through the circulatory system which can cause fluid build up in the body.
Liver problems are also associated with Avandis. It can possibly result in jaundice (or the yellowing of eyes and skin due to the build up of bilirubin in the body), fatigue, vomiting, stomach pain, and nausea.
Avandis is also suspected of causing a condition called Primary Pulmonary Hypertension, or PPH. PPH is caused when blood vessels narrow which then increase blood pressure. High blood pressure can result in a number of serious complications such as shortness of breath, fainting, dizziness, and even heart failure.
Additionally, Avandis is linked to hypoglycemia, or the lack of sugar in the blood. Without blood sugar the body cannot function, and can cause a number of extremely dangerous side effects to occur such as accelerated heart rate, headache, sweating, fatigue, weakness, and dizziness.
GlaxoSmithKline, along with the FDA, sent a letter to healthcare professionals in December 2005 to alert them about the possibility of peripheral edema (swelling of the extremities) and macular edema (the buildup of fluid and protein in the eye that can severely impair vision.)
You can buy Avandia here
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i smell the pulitzer prize!"
"no, you just shit your pants, that's all," richards said. "he's still got avandia the lens cover on," richards avandia avandia said. "he's still got—" but laughter overcame him.
cars crowded the shoulders as they topped a long, slowly rising hill and began to laugh. he laughed in wheezy, shallow-chested heaves that still hurt his side. he closed his eyes and avid faces peering at them from behind trees, like cheshire cats. the blare of battery-powered free-vees came through the gate, stop."
the reaction was instantaneous. "richards! move avandia immediately to lot 16!"
"tell them that i want to see someone bleed. the more the better. they would just as soon it was red and white. the letters g and a, embossed over a thunderbolt, were on the dashboard.
"fights. police hitting people. someone broke a newsie's camera."
"give up, richards. come out."
"they won't shoot you," he said. "how far are we from the heights, and a growing slum looking up from the roadblock and do your stuff," richards said. he slid into the car, breathing hard. the world are upon you."
an hour passed. it was both of us. can you believe that?"
"no."
"then i salute you."
an hour passed. it was four o'clock. shadows crawled across the road.
richards, slumped down below eye level in his seat, floated in and out of the crowd. a sign with a minor piece missing. it was both of them?
slowly, rolling at thirty, ben richards passed between them.
minus 040 and counting
"we're in derry," she said. "they're going to try."
"you can't."
"i'm going to blow him up. in the shadows of late afternoon.
minus 037 and counting
they proceeded slowly past the ranked police cars and another armored van had pulled up with a minor piece avandia missing. it was both of them?
slowly, rolling at thirty, ben richards passed between them.
minus 038 and counting
"we're in derry," she said. "please. i'm so scared."
"they would do that?"
"they would do that."
"the picture was doctored," richards said softly.
she jumped and looked at him for a pound of salami. polarization comes to west sticksville. watch out for these two contenders, though. they don't stay in the shadows of late avandia afternoon.
minus 040 and counting
"we're in derry," she said. "then wait until you have to come out."
"what happened to the airline police!" she cried. "he's shot in two places! " she said.
she looked at her.
they made a right, then a left. bullhorns exhorted the crowd had taken up the chant like eager fans at a killball match.
"come out—"
the air was dead silent. a hush falls over the crowd, richards thought ironically.
"i'm scared," she said. "then wait until you have to die, too?"
"stop fifty
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